276 search results - page 4 / 56 » Methods for Predicting Target Sites of Transcription Factors |
NAR
2006
13 years 7 months ago
2006
Individual zinc finger (ZF) domains that recognize DNA triplets with high specificity and affinity can be used to create designer transcription factors and nucleases that are spec...
BMCBI
2007
13 years 7 months ago
2007
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
BMCBI
2010
2010
An intuitionistic approach to scoring DNA sequences against transcription factor binding site motifs
13 years 7 months ago
Background: Transcription factors (TFs) control transcription by binding to specific regions of DNA called transcription factor binding sites (TFBSs). The identification of TFBSs ...
BMCBI
2008
13 years 7 months ago
2008
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
BMCBI
2008
13 years 7 months ago
2008
Background: Eukaryotic cell cycle is a complex process and is precisely regulated at many levels. Many genes specific to the cell cycle are regulated transcriptionally and are exp...