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» Microarray results: how accurate are they
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BMCBI
2005
189views more  BMCBI 2005»
13 years 9 months ago
Quantitative inference of dynamic regulatory pathways via microarray data
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
Wen-Chieh Chang, Chang-Wei Li, Bor-Sen Chen
BMCBI
2007
141views more  BMCBI 2007»
13 years 9 months ago
On the origin and evolution of biosynthetic pathways: integrating microarray data with structure and organization of the Common
Background: The lysine, threonine, and methionine biosynthetic pathways share the three initial enzymatic steps, which are referred to as the Common Pathway (CP). In Escherichia c...
Marco Fondi, Matteo Brilli, Renato Fani
BMCBI
2006
110views more  BMCBI 2006»
13 years 10 months ago
Design of a combinatorial DNA microarray for protein-DNA interaction studies
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...
Julian Mintseris, Michael B. Eisen
ARITH
2007
IEEE
14 years 4 months ago
How to Ensure a Faithful Polynomial Evaluation with the Compensated Horner Algorithm
The compensated Horner algorithm improves the accuracy of polynomial evaluation in IEEE-754 floating point arithmetic: the computed result is as accurate as if it was computed wi...
Philippe Langlois, Nicolas Louvet
BMCBI
2007
151views more  BMCBI 2007»
13 years 10 months ago
A statistical method to incorporate biological knowledge for generating testable novel gene regulatory interactions from microar
Background: The incorporation of prior biological knowledge in the analysis of microarray data has become important in the reconstruction of transcription regulatory networks in a...
Peter Larsen, Eyad Almasri, Guanrao Chen, Yang Dai