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BMCBI
2006
108views more  BMCBI 2006»
15 years 4 months ago
A new pooling strategy for high-throughput screening: the Shifted Transversal Design
Background: In binary high-throughput screening projects where the goal is the identification of low-frequency events, beyond the obvious issue of efficiency, false positives and ...
Nicolas Thierry-Mieg
BMCBI
2007
148views more  BMCBI 2007»
15 years 4 months ago
fREDUCE: Detection of degenerate regulatory elements using correlation with expression
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...
BMCBI
2007
148views more  BMCBI 2007»
15 years 4 months ago
WeederH: an algorithm for finding conserved regulatory motifs and regions in homologous sequences
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Giulio Pavesi, Federico Zambelli, Graziano Pesole
BMCBI
2004
98views more  BMCBI 2004»
15 years 4 months ago
Incidence of "quasi-ditags" in catalogs generated by Serial Analysis of Gene Expression (SAGE)
Background: Serial Analysis of Gene Expression (SAGE) is a functional genomic technique that quantitatively analyzes the cellular transcriptome. The analysis of SAGE libraries rel...
Sergey V. Anisimov, Alexei A. Sharov
BMCBI
2002
131views more  BMCBI 2002»
15 years 4 months ago
Efficient Boolean implementation of universal sequence maps (bUSM)
Background: Recently, Almeida and Vinga offered a new approach for the representation of arbitrary discrete sequences, referred to as Universal Sequence Maps (USM), and discussed ...
John Schwacke, Jonas S. Almeida