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ISBI
2011
IEEE
13 years 8 days ago
Automated lineage tree reconstruction from Caenorhabditis elegans image data using particle filtering based cell tracking
Caenorhabditis elegans is an important model organism for the study of molecular mechanisms of development and disease processes, due to its well-known genome and invariant cell l...
Noemí Carranza-Herrezuelo, Ihor Smal, Oleh ...
BMCBI
2006
240views more  BMCBI 2006»
13 years 8 months ago
Statistical analysis of real-time PCR data
Background: Even though real-time PCR has been broadly applied in biomedical sciences, data processing procedures for the analysis of quantitative real-time PCR are still lacking;...
Joshua S. Yuan, Ann Reed, Feng Chen, C. Neal Stewa...
BMCBI
2002
214views more  BMCBI 2002»
13 years 8 months ago
Automated modelling of signal transduction networks
Background: Intracellular signal transduction is achieved by networks of proteins and small molecules that transmit information from the cell surface to the nucleus, where they ul...
Martin Steffen, Allegra Petti, John Aach, Patrik D...
BMCBI
2007
186views more  BMCBI 2007»
13 years 8 months ago
Modeling human cancer-related regulatory modules by GA-RNN hybrid algorithms
Background: Modeling cancer-related regulatory modules from gene expression profiling of cancer tissues is expected to contribute to our understanding of cancer biology as well as...
Jung-Hsien Chiang, Shih-Yi Chao
BMCBI
2005
201views more  BMCBI 2005»
13 years 8 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota