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BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
15 years 2 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...
BMCBI
2010
129views more  BMCBI 2010»
15 years 2 months ago
Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
Mindaugas Margelevicius, Ceslovas Venclovas
143
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BMCBI
2011
14 years 6 months ago
Inference of Chromosome-Specific Copy Numbers Using Population Haplotypes
Background: Using microarray and sequencing platforms, a large number of copy number variations (CNVs) have been identified in humans. In practice, because our human genome is a d...
Yao-Ting Huang, Min-Han Wu
ICA
2004
Springer
15 years 7 months ago
Blind Maximum Likelihood Separation of a Linear-Quadratic Mixture
Abstract. We proposed recently a new method for separating linearquadratic mixtures of independent real sources, based on parametric identification of a recurrent separating struc...
Shahram Hosseini, Yannick Deville
117
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BMCBI
2007
128views more  BMCBI 2007»
15 years 2 months ago
Model order selection for bio-molecular data clustering
Background: Cluster analysis has been widely applied for investigating structure in bio-molecular data. A drawback of most clustering algorithms is that they cannot automatically ...
Alberto Bertoni, Giorgio Valentini