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BMCBI
2007
166views more  BMCBI 2007»
13 years 6 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
13 years 6 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...
CIKM
2010
Springer
13 years 4 months ago
Regularization and feature selection for networked features
In the standard formalization of supervised learning problems, a datum is represented as a vector of features without prior knowledge about relationships among features. However, ...
Hongliang Fei, Brian Quanz, Jun Huan
BMCBI
2005
84views more  BMCBI 2005»
13 years 6 months ago
A method of precise mRNA/DNA homology-based gene structure prediction
Background: Accurate and automatic gene finding and structural prediction is a common problem in bioinformatics, and applications need to be capable of handling non-canonical spli...
Alexander G. Churbanov, Mark Pauley, Daniel Quest,...
BIBE
2005
IEEE
115views Bioinformatics» more  BIBE 2005»
14 years 10 days ago
GOMIT: A Generic and Adaptive Annotation Algorithm Based on Gene Ontology Term Distributions
We address the issue of providing highly informative annotations using information revealed by the structured vocabularies of Gene Ontology (GO). For a target, a set of candidate ...
In-Yee Lee, Jan-Ming Ho, Ming-Syan Chen