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BMCBI
2008
132views more  BMCBI 2008»
13 years 10 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
BMCBI
2010
133views more  BMCBI 2010»
13 years 10 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
BMCBI
2008
118views more  BMCBI 2008»
13 years 10 months ago
Kismeth: Analyzer of plant methylation states through bisulfite sequencing
Background: There is great interest in probing the temporal and spatial patterns of cytosine methylation states in genomes of a variety of organisms. It is hoped that this will sh...
Eyal Gruntman, Yijun Qi, R. Keith Slotkin, Ted Roe...
BMCBI
2008
160views more  BMCBI 2008»
13 years 10 months ago
VariVis: a visualisation toolkit for variation databases
Background: With the completion of the Human Genome Project and recent advancements in mutation detection technologies, the volume of data available on genetic variations has rise...
Timothy D. Smith, Richard G. H. Cotton
BMCBI
2007
181views more  BMCBI 2007»
13 years 10 months ago
Versatile annotation and publication quality visualization of protein complexes using POLYVIEW-3D
Background: Macromolecular visualization as well as automated structural and functional annotation tools play an increasingly important role in the post-genomic era, contributing ...
Aleksey A. Porollo, Jaroslaw Meller
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