Pfam contains multiple alignments and hidden Markov model based profiles (HMM-profiles) of complete protein domains. The definition of domain boundaries, family members and alignm...
Erik L. L. Sonnhammer, Sean R. Eddy, Ewan Birney, ...
In this paper, we present a graphical model for protein secondary structure prediction. This model extends segmental semi-Markov models (SSMM) to exploit multiple sequence alignme...
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
Background: The increasing number of protein sequences and 3D structure obtained from genomic initiatives is leading many of us to focus on proteomics, and to dedicate our experim...
Identifying effective tutorial strategies is a key problem for tutorial dialogue systems research. Ongoing work in human-human tutorial dialogue continues to reveal the complex phe...
Kristy Elizabeth Boyer, Eunyoung Ha, Michael D. Wa...