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» Models and Methods in Comparative Genomics
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BIBE
2007
IEEE
148views Bioinformatics» more  BIBE 2007»
14 years 4 months ago
A New Smoothing Model for Analyzing Array CGH Data
—Array based Comparative Genomic Hybridization (CGH) is a molecular cytogenetic method for the detection of chromosomal imbalances and it has been extensively used for studying c...
Nha Nguyen, Heng Huang, Soontorn Oraintara, An P. ...
BMCBI
2007
113views more  BMCBI 2007»
13 years 9 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu
BCB
2010
156views Bioinformatics» more  BCB 2010»
13 years 4 months ago
RepFrag: a graph based method for finding repeats and transposons from fragmented genomes
Growing sequencing and assembly efforts have been met by the advances in high throughput machines. However, the presence of massive amounts of repeats and transposons complicates ...
Nirmalya Bandyopadhyay, A. Mark Settles, Tamer Kah...
BMCBI
2008
108views more  BMCBI 2008»
13 years 10 months ago
Supervised Lowess normalization of comparative genome hybridization data - application to lactococcal strain comparisons
Background: Array-based comparative genome hybridization (aCGH) is commonly used to determine the genomic content of bacterial strains. Since prokaryotes in general have less cons...
Sacha A. F. T. van Hijum, Richard J. S. Baerends, ...
RECOMB
2009
Springer
14 years 4 months ago
Reconstructing Histories of Complex Gene Clusters on a Phylogeny
Abstract. Clusters of genes that have evolved by repeated segmental duplication present difficult challenges throughout genomic analysis, from sequence assembly to functional analy...
Tomás Vinar, Brona Brejová, Giltae S...