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» Models and Methods in Comparative Genomics
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BIOINFORMATICS
2011
13 years 4 months ago
Modeling and comparing the organization of circular genomes
Grace S. Shieh, Shurong Zheng, Richard A. Johnson,...
BMCBI
2006
92views more  BMCBI 2006»
13 years 10 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
BIOINFORMATICS
2010
138views more  BIOINFORMATICS 2010»
13 years 10 months ago
Robust unmixing of tumor states in array comparative genomic hybridization data
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...
ESANN
2006
13 years 11 months ago
Sanger-driven MDSLocalize - a comparative study for genomic data
Multidimensional scaling (MDS) methods are designed to establish a one-to-one correspondence of input-output relationships. While the input may be given as high-dimensional data it...
Marc Strickert, Nese Sreenivasulu, Udo Seiffert
BMCBI
2007
104views more  BMCBI 2007»
13 years 9 months ago
A response to Yu et al. "A forward-backward fragment assembling algorithm for the identification of genomic amplification and de
Background: Yu et al. (BMC Bioinformatics 2007,8: 145+) have recently compared the performance of several methods for the detection of genomic amplification and deletion breakpoin...
Oscar M. Rueda, Ramón Díaz-Uriarte