Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
Background: Microarrays used for gene expression studies yield large amounts of data. The processing of such data typically leads to lists of differentially-regulated genes. A com...
G. W. Patton, Robert M. Stephens, I. A. Sidorov, X...
Many real world data are sampled functions. As shown by Functional Data Analysis (FDA) methods, spectra, time series, images, gesture recognition data, etc. can be processed more e...
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Background: Many important high throughput projects use in situ hybridization and may require the analysis of images of spatial cross sections of organisms taken with cellular lev...
Manjunatha Jagalur, Chris Pal, Erik G. Learned-Mil...