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CORR
2006
Springer
153views Education» more  CORR 2006»
13 years 7 months ago
Genetic Programming, Validation Sets, and Parsimony Pressure
Fitness functions based on test cases are very common in Genetic Programming (GP). This process can be assimilated to a learning task, with the inference of models from a limited n...
Christian Gagné, Marc Schoenauer, Marc Pari...
BMCBI
2007
94views more  BMCBI 2007»
13 years 7 months ago
Model based analysis of real-time PCR data from DNA binding dye protocols
Background: Reverse transcription followed by real-time PCR is widely used for quantification of specific mRNA, and with the use of double-stranded DNA binding dyes it is becoming...
Mariano J. Alvarez, Guillermo J. Vila-Ortiz, Maria...
BMCBI
2007
137views more  BMCBI 2007»
13 years 7 months ago
PlnTFDB: an integrative plant transcription factor database
Background: Transcription factors (TFs) are key regulatory proteins that enhance or repress the transcriptional rate of their target genes by binding to specific promoter regions ...
Diego Mauricio Riaño-Pachón, Sloboda...
BMCBI
2007
144views more  BMCBI 2007»
13 years 7 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...
BMCBI
2007
77views more  BMCBI 2007»
13 years 7 months ago
The reactive metabolite target protein database (TPDB) - a web-accessible resource
Background: The toxic effects of many simple organic compounds stem from their biotransformation to chemically reactive metabolites which bind covalently to cellular proteins. To ...
Robert P. Hanzlik, Yakov M. Koen, Bhargav Theertha...