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BMCBI
2007
129views more  BMCBI 2007»
13 years 7 months ago
A novel approach to sequence validating protein expression clones with automated decision making
Background: Whereas the molecular assembly of protein expression clones is readily automated and routinely accomplished in high throughput, sequence verification of these clones i...
Elena Taycher, Andreas Rolfs, Yanhui Hu, Dongmei Z...
BMCBI
2006
120views more  BMCBI 2006»
13 years 7 months ago
Optimizing amino acid substitution matrices with a local alignment kernel
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
Hiroto Saigo, Jean-Philippe Vert, Tatsuya Akutsu
BMCBI
2006
117views more  BMCBI 2006»
13 years 7 months ago
Gene Designer: a synthetic biology tool for constructing artificial DNA segments
Background: Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization, RNAi re...
Alan Villalobos, Jon E. Ness, Claes Gustafsson, Je...
BMCBI
2006
128views more  BMCBI 2006»
13 years 7 months ago
Model-driven user interfaces for bioinformatics data resources: regenerating the wheel as an alternative to reinventing it
Background: The proliferation of data repositories in bioinformatics has resulted in the development of numerous interfaces that allow scientists to browse, search and analyse the...
Kevin L. Garwood, Christopher Garwood, Cornelia He...
DSS
2006
140views more  DSS 2006»
13 years 7 months ago
Access control and audit model for the multidimensional modeling of data warehouses
Due to the sensitive data contained in Data Warehouses (DW), it is essential to specify security measures from the early stages of the DW design and enforce them. Traditional acce...
Eduardo Fernández-Medina, Juan Trujillo, Ro...