258 search results - page 25 / 52 » Multiobjectivizing the HP Model for Protein Structure Predic... |
BMCBI
2007
13 years 7 months ago
2007
Background: During the past decades, research and development in drug discovery have attracted much attention and efforts. However, only 324 drug targets are known for clinical dr...
BIOINFORMATICS
2010
13 years 7 months ago
2010
Motivation: To test whether protein folding constraints and secondary structure sequence preferences significantly reduce the space of amino acid words in proteins, we compared th...
BMCBI
2006
13 years 7 months ago
2006
Background: The emerging field of integrative bioinformatics provides the tools to organize and systematically analyze vast amounts of highly diverse biological data and thus allo...
CSB
2003
IEEE
14 years 28 days ago
2003
IEEE
Recognition of a protein’s fold provides valuable information about its function. While many sequence-based homology prediction methods exist, an important challenge remains: tw...
BMCBI
2008
13 years 7 months ago
2008
Background: Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of f...