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BMCBI
2011
12 years 11 months ago
Improving pan-genome annotation using whole genome multiple alignment
Background: Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology. Genome annotations c...
Samuel V. Angiuoli, Julie C. Dunning Hotopp, Steve...
BMCBI
2007
147views more  BMCBI 2007»
13 years 7 months ago
MaxAlign: maximizing usable data in an alignment
Background: The presence of gaps in an alignment of nucleotide or protein sequences is often an inconvenience for bioinformatical studies. In phylogenetic and other analyses, for ...
Rodrigo Gouveia-Oliveira, Peter Wad Sackett, Ander...
NAR
2006
119views more  NAR 2006»
13 years 7 months ago
HHsenser: exhaustive transitive profile search using HMM-HMM comparison
HHsenser is the first server to offer exhaustive intermediate profile searches, which it combines with pairwise comparison of hidden Markov models. Starting from a single protein ...
Johannes Söding, Michael Remmert, Andreas Bie...
DEXA
2007
Springer
150views Database» more  DEXA 2007»
14 years 1 months ago
Sequence Alignment as a Database Technology Challenge
Abstract. Sequence alignment is an important task for molecular biologists. Because alignment basically deals with approximate string matching on large biological sequence collecti...
Hans Philippi
APBC
2004
13 years 9 months ago
EMAGEN: An Efficient Approach to Multiple Whole Genome Alignment
Following advances in biotechnology, many new whole genome sequences are becoming available every year. A lot of useful information can be derived from the alignment and compariso...
Jitender S. Deogun, Jingyi Yang, Fangrui Ma