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BMCBI
2006
120views more  BMCBI 2006»
13 years 7 months ago
An improved distance measure between the expression profiles linking co-expression and co-regulation in mouse
Background: Many statistical algorithms combine microarray expression data and genome sequence data to identify transcription factor binding motifs in the low eukaryotic genomes. ...
Ryung S. Kim, Hongkai Ji, Wing Hung Wong
BMCBI
2006
113views more  BMCBI 2006»
13 years 7 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
BMCBI
2007
215views more  BMCBI 2007»
13 years 7 months ago
Learning causal networks from systems biology time course data: an effective model selection procedure for the vector autoregres
Background: Causal networks based on the vector autoregressive (VAR) process are a promising statistical tool for modeling regulatory interactions in a cell. However, learning the...
Rainer Opgen-Rhein, Korbinian Strimmer
ISIPTA
1999
IEEE
116views Mathematics» more  ISIPTA 1999»
13 years 11 months ago
On the Distribution of Natural Probability Functions
The purpose of this note is to describe the underlying insights and results obtained by the authors, and others, in a series of papers aimed at modelling the distribution of `natu...
Jeff B. Paris, Paul N. Watton, George M. Wilmers
GECCO
2006
Springer
151views Optimization» more  GECCO 2006»
13 years 11 months ago
Sporadic model building for efficiency enhancement of hierarchical BOA
This paper describes and analyzes sporadic model building, which can be used to enhance the efficiency of the hierarchical Bayesian optimization algorithm (hBOA) and other advance...
Martin Pelikan, Kumara Sastry, David E. Goldberg