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» NEC for Gene Expression Analysis
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BMCBI
2011
14 years 10 months ago
The PathOlogist: An Automated Tool for Pathway-Centric Analysis
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...
159
Voted
IMSCCS
2006
IEEE
15 years 10 months ago
Frequency Distribution of TATA Box and Extension Sequences on Human Promoters
Background: TATA box is one of the most important transcription factor binding sites. But the exact sequences of TATA box are still not very clear. Results: In this study, we cond...
Wei Shi, Wanlei Zhou
138
Voted
COMPLIFE
2005
Springer
15 years 9 months ago
Robust Perron Cluster Analysis for Various Applications in Computational Life Science
In the present paper we explain the basic ideas of Robust Perron Cluster Analysis (PCCA+) and exemplify the different application areas of this new and powerful method. Recently, ...
Marcus Weber, Susanna Kube
RECOMB
2007
Springer
15 years 10 months ago
Network Legos: Building Blocks of Cellular Wiring Diagrams
Publicly-available data sets provide detailed and large-scale information on multiple types of molecular interaction networks in a number of model organisms. These multi-modal univ...
T. M. Murali, Corban G. Rivera
BMCBI
2008
106views more  BMCBI 2008»
15 years 4 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...