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BIOINFORMATICS
2005
140views more  BIOINFORMATICS 2005»
13 years 8 months ago
Profile-based direct kernels for remote homology detection and fold recognition
Motivation: Remote homology detection between protein sequences is a central problem in computational biology. Supervised learning algorithms based on support vector machines are ...
Huzefa Rangwala, George Karypis
RECOMB
1999
Springer
14 years 21 days ago
Fast detection of common geometric substructure in proteins
We consider the problem of identifying common three-dimensional substructures between proteins. Our method is based on comparing the shape of the α-carbon backbone structures of ...
L. Paul Chew, Daniel P. Huttenlocher, Klara Kedem,...
ASC
2008
13 years 8 months ago
Info-fuzzy algorithms for mining dynamic data streams
Most data mining algorithms assume static behavior of the incoming data. In the real world, the situation is different and most continuously collected data streams are generated by...
Lior Cohen, Gil Avrahami, Mark Last, Abraham Kande...
ISMB
2008
13 years 10 months ago
Classification of arrayCGH data using fused SVM
Motivation: Array-based comparative genomic hybridization (arrayCGH) has recently become a popular tool to identify DNA copy number variations along the genome. These profiles are...
Franck Rapaport, Emmanuel Barillot, Jean-Philippe ...
RECOMB
2004
Springer
14 years 8 months ago
Designing multiple simultaneous seeds for DNA similarity search
The challenge of similarity search in massive DNA sequence databases has inspired major changes in BLAST-style alignment tools, which accelerate search by inspecting only pairs of...
Yanni Sun, Jeremy Buhler