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RECOMB
2009
Springer
14 years 8 months ago
New Perspectives on Gene Family Evolution: Losses in Reconciliation and a Link with Supertrees
Reconciliation between a set of gene trees and a species tree is the most commonly used approach to infer the duplication and loss events in the evolution of gene families, given a...
Cedric Chauve, Nadia El-Mabrouk
BMCBI
2010
135views more  BMCBI 2010»
13 years 7 months ago
HDAPD: a web tool for searching the disease-associated protein structures
Background: The protein structures of the disease-associated proteins are important for proceeding with the structure-based drug design to against a particular disease. Up until n...
Yi-Ruen Lin, Hsin-Yuan Wei, Tsung-Lin Tsai, Thy-Ho...
CIE
2010
Springer
13 years 10 months ago
A Faster Algorithm for Finding Minimum Tucker Submatrices
A binary matrix has the Consecutive Ones Property (C1P) if its columns can be ordered in such a way that all 1s on each row are consecutive. Algorithmic issues of the C1P are centr...
Guillaume Blin, Romeo Rizzi, Stéphane Viale...
BMCBI
2010
178views more  BMCBI 2010»
13 years 7 months ago
Applications of a formal approach to decipher discrete genetic networks
Background: A growing demand for tools to assist the building and analysis of biological networks exists in systems biology. We argue that the use of a formal approach is relevant...
Fabien Corblin, Eric Fanchon, Laurent Trilling
ALGORITHMICA
1999
84views more  ALGORITHMICA 1999»
13 years 7 months ago
Computational Approaches to Drug Design
Abstract. The rational approach to pharmaceutical drug design begins with an investigation of the relationship between chemical structure and biological activity. Information gaine...
Paul W. Finn, Lydia E. Kavraki