126 search results - page 10 / 26 » Next generation sequencing in functional genomics |
BMCBI
2007
13 years 7 months ago
2007
Background: The structure annotation of a genome is based either on ab initio methodologies or on similaritiy searches versus molecules that have been already annotated. Ab initio...
RECOMB
2008
Springer
14 years 7 months ago
2008
Springer
Abstract. Clusters of genes that evolved from single progenitors via repeated segmental duplications present significant challenges to the generation of a truly complete human geno...
BMCBI
2010
13 years 7 months ago
2010
Background: The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of differe...
BMCBI
2006
13 years 7 months ago
2006
Background: The rapidly increasing speed with which genome sequence data can be generated will be accompanied by an exponential increase in the number of sequenced eukaryotes. Wit...
BMCBI
2006
13 years 7 months ago
2006
Background: The number of sequences compiled in many genome projects is growing exponentially, but most of them have not been characterized experimentally. An automatic annotation...