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BMCBI
2008
120views more  BMCBI 2008»
13 years 8 months ago
E-CAI: a novel server to estimate an expected value of Codon Adaptation Index (eCAI)
Background: The Codon Adaptation Index (CAI) is a measure of the synonymous codon usage bias for a DNA or RNA sequence. It quantifies the similarity between the synonymous codon u...
Pere Puigbò, Ignacio G. Bravo, Santiago Gar...
BMCBI
2007
171views more  BMCBI 2007»
13 years 8 months ago
An open source infrastructure for managing knowledge and finding potential collaborators in a domain-specific subset of PubMed,
Background: Identifying relevant research in an ever-growing body of published literature is becoming increasingly difficult. Establishing domain-specific knowledge bases may be a...
Wei Yu, Ajay Yesupriya, Anja Wulf, Junfeng Qu, Mui...
BMCBI
2010
243views more  BMCBI 2010»
13 years 8 months ago
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data
Background: Visualization of DNA microarray data in two or three dimensional spaces is an important exploratory analysis step in order to detect quality issues or to generate new ...
Christoph Bartenhagen, Hans-Ulrich Klein, Christia...
BMCBI
2007
108views more  BMCBI 2007»
13 years 8 months ago
Computer-aided identification of polymorphism sets diagnostic for groups of bacterial and viral genetic variants
Background: Single nucleotide polymorphisms (SNPs) and genes that exhibit presence/absence variation have provided informative marker sets for bacterial and viral genotyping. Iden...
Erin P. Price, John Inman-Bamber, Venugopal Thiruv...
BMCBI
2007
102views more  BMCBI 2007»
13 years 8 months ago
Multivariate Analysis and Visualization of Splicing Correlations in Single-Gene Transcriptomes
Background: RNA metabolism, through 'combinatorial splicing', can generate enormous structural diversity in the proteome. Alternative domains may interact, however, with...
Mark C. Emerick, Giovanni Parmigiani, William S. A...