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BMCBI
2010
126views more  BMCBI 2010»
13 years 8 months ago
Simulation of a Petri net-based Model of the Terpenoid Biosynthesis Pathway
Background: The development and simulation of dynamic models of terpenoid biosynthesis has yielded a systems perspective that provides new insights into how the structure of this ...
Aliah Hazmah Hawari, Zeti-Azura Mohamed-Hussein
BMCBI
2007
127views more  BMCBI 2007»
13 years 8 months ago
A Latent Variable Approach for Meta-Analysis of Gene Expression Data from Multiple Microarray Experiments
Background: With the explosion in data generated using microarray technology by different investigators working on similar experiments, it is of interest to combine results across...
Hyungwon Choi, Ronglai Shen, Arul M. Chinnaiyan, D...
BMCBI
2008
163views more  BMCBI 2008»
13 years 8 months ago
ProfileGrids as a new visual representation of large multiple sequence alignments: a case study of the RecA protein family
Background: Multiple sequence alignments are a fundamental tool for the comparative analysis of proteins and nucleic acids. However, large data sets are no longer manageable for v...
Alberto I. Roca, Albert E. Almada, Aaron C. Abajia...
BMCBI
2010
116views more  BMCBI 2010»
13 years 8 months ago
Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences
Background: Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the eff...
Jeffry D. Sander, Deepak Reyon, Morgan L. Maeder, ...
BMCBI
2008
105views more  BMCBI 2008»
13 years 8 months ago
Objective and automated protocols for the evaluation of biomedical search engines using No Title Evaluation protocols
Background: The evaluation of information retrieval techniques has traditionally relied on human judges to determine which documents are relevant to a query and which are not. Thi...
Fabien Campagne