207 search results - page 38 / 42 » On Bootstrapping the ROC Curve |
BMCBI
2010
13 years 8 months ago
2010
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
BMCBI
2010
13 years 8 months ago
2010
Background: Meta-analysis methods exist for combining multiple microarray datasets. However, there are a wide range of issues associated with microarray meta-analysis and a limite...
BMCBI
2007
13 years 8 months ago
2007
Background: Independently derived expression profiles of the same biological condition often have few genes in common. In this study, we created populations of expression profiles...
BMCBI
2007
13 years 8 months ago
2007
Background: In a previous study, we demonstrated that some essential proteins from pathogenic organisms contained sizable insertions/deletions (indels) when aligned to human prote...
BMCBI
2007
13 years 8 months ago
2007
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...