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» On Compressibility of Protein Sequences
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BMCBI
2010
109views more  BMCBI 2010»
15 years 6 months ago
Pripper: prediction of caspase cleavage sites from whole proteomes
Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
Mirva Piippo, Niina Lietzén, Olli Nevalaine...
222
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BMCBI
2008
200views more  BMCBI 2008»
15 years 6 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
148
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BMCBI
2007
145views more  BMCBI 2007»
15 years 6 months ago
Genome bioinformatic analysis of nonsynonymous SNPs
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
David F. Burke, Catherine L. Worth, Eva-Maria Prie...
161
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BMCBI
2010
150views more  BMCBI 2010»
15 years 5 months ago
DeltaProt: a software toolbox for comparative genomics
Background: Statistical bioinformatics is the study of biological data sets obtained by new micro-technologies by means of proper statistical methods. For a better understanding o...
Steinar Thorvaldsen, Tor Flå, Nils Willassen
170
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NAR
2011
277views Computer Vision» more  NAR 2011»
14 years 9 months ago
The 2011 Nucleic Acids Research Database Issue and the online Molecular Biology Database Collection
The current 18th Database Issue of Nucleic Acids Research features descriptions of 96 new and 83 updated online databases covering various areas of molecular biology. It includes ...
Michael Y. Galperin, Guy Cochrane