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» On Conceptualization as a Systematic Process
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BMCBI
2010
122views more  BMCBI 2010»
13 years 8 months ago
An automated framework for understanding structural variations in the binding grooves of MHC class II molecules
Background: MHC/HLA class II molecules are important components of the immune system and play a critical role in processes such as phagocytosis. Understanding peptide recognition ...
Kalidas Yeturu, Tapani Utriainen, Graham J. L. Kem...
BMCBI
2006
96views more  BMCBI 2006»
13 years 8 months ago
Bayesian detection of periodic mRNA time profiles without use of training examples
Background: Detection of periodically expressed genes from microarray data without use of known periodic and non-periodic training examples is an important problem, e.g. for ident...
Claes R. Andersson, Anders Isaksson, Mats G. Gusta...
BMCBI
2006
131views more  BMCBI 2006»
13 years 8 months ago
The statistics of identifying differentially expressed genes in Expresso and TM4: a comparison
Background: Analysis of DNA microarray data takes as input spot intensity measurements from scanner software and returns differential expression of genes between two conditions, t...
Allan A. Sioson, Shrinivasrao P. Mane, Pinghua Li,...
BMCBI
2007
123views more  BMCBI 2007»
13 years 8 months ago
Normalization and experimental design for ChIP-chip data
Background: Chromatin immunoprecipitation on tiling arrays (ChIP-chip) has been widely used to investigate the DNA binding sites for a variety of proteins on a genome-wide scale. ...
Shouyong Peng, Artyom A. Alekseyenko, Erica Larsch...
PPL
2008
185views more  PPL 2008»
13 years 8 months ago
On Design and Application Mapping of a Network-on-Chip(NoC) Architecture
As the number of integrated IP cores in the current System-on-Chips (SoCs) keeps increasing, communication requirements among cores can not be sufficiently satisfied using either ...
Jun Ho Bahn, Seung Eun Lee, Yoon Seok Yang, Jungso...