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BMCBI
2010
105views more  BMCBI 2010»
13 years 10 months ago
GWAMA: software for genome-wide association meta-analysis
Background: Despite the recent success of genome-wide association studies in identifying novel loci contributing effects to complex human traits, such as type 2 diabetes and obesi...
Reedik Mägi, Andrew P. Morris
BMCBI
2010
138views more  BMCBI 2010»
13 years 10 months ago
A database and API for variation, dense genotyping and resequencing data
Background: Advances in sequencing and genotyping technologies are leading to the widespread availability of multi-species variation data, dense genotype data and large-scale rese...
Daniel Rios, William M. McLaren, Yuan Chen, Ewan B...
BMCBI
2007
131views more  BMCBI 2007»
13 years 10 months ago
FUNC: a package for detecting significant associations between gene sets and ontological annotations
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...
Kay Prüfer, Bjoern Muetzel, Hong Hai Do, Gunt...
BMCBI
2008
112views more  BMCBI 2008»
13 years 10 months ago
Normalization for triple-target microarray experiments
Background: Most microarray studies are made using labelling with one or two dyes which allows the hybridization of one or two samples on the same slide. In such experiments, the ...
Marie-Laure Martin-Magniette, Julie Aubert, Avner ...
BMCBI
2007
123views more  BMCBI 2007»
13 years 10 months ago
PedGenie: meta genetic association testing in mixed family and case-control designs
Background-: PedGenie software, introduced in 2006, includes genetic association testing of cases and controls that may be independent or related (nuclear families or extended ped...
Karen Curtin, Jathine Wong, Kristina Allen-Brady, ...