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» On Timed Models of Gene Networks
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BMCBI
2010
143views more  BMCBI 2010»
13 years 8 months ago
Learning gene regulatory networks from only positive and unlabeled data
Background: Recently, supervised learning methods have been exploited to reconstruct gene regulatory networks from gene expression data. The reconstruction of a network is modeled...
Luigi Cerulo, Charles Elkan, Michele Ceccarelli
TIT
2010
97views Education» more  TIT 2010»
13 years 2 months ago
Periodic orbits and equilibria in glass models for gene regulatory networks
Abstract--Glass models are frequently used to model gene regulatory networks. A distinct feature of the Glass model is that its dynamics can be formalized as paths through multi-di...
Igor Zinovik, Yury Chebiryak, Daniel Kroening
RECOMB
2005
Springer
14 years 8 months ago
Comparative Systems Biology of the Sporulation Initiation Network in Prokaryotes
Many years of experimental and computational molecular biology of model organisms such as Escherichia coli and Saccharomyces cerevisiae has elucidated the gene regulatory network i...
Michiel J. L. de Hoon, Dennis Vitkup
BIOINFORMATICS
2011
13 years 2 months ago
Inverse perturbation for optimal intervention in gene regulatory networks
Motivation: Analysis and intervention in the dynamics of gene regulatory networks is at the heart of emerging efforts in the development of modern treatment of numerous ailments i...
Nidhal Bouaynaya, Roman Shterenberg, Dan Schonfeld
BMCBI
2010
104views more  BMCBI 2010»
13 years 8 months ago
Bidirectional best hit r-window gene clusters
Background: Conserved gene clusters are groups of genes that are located close to one another in the genomes of several species. They tend to code for proteins that have a functio...
Melvin Zhang, Hon Wai Leong