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BMCBI
2005
13 years 7 months ago
2005
Background: Regions of interest identified through genetic linkage studies regularly exceed 30 centimorgans in size and can contain hundreds of genes. Traditionally this number is...
BMCBI
2005
13 years 7 months ago
2005
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
BMCBI
2005
13 years 7 months ago
2005
: One of the most evident achievements of bioinformatics is the development of methods that transfer biological knowledge from characterised proteins to uncharacterised sequences. ...
BMCBI
2004
13 years 7 months ago
2004
Background: Several aspects of microarray data analysis are dependent on identification of genes expressed at or near the limits of detection. For example, regression-based normal...
BMCBI
2004
13 years 7 months ago
2004
Background: Conserved protein sequence motifs are short stretches of amino acid sequence patterns that potentially encode the function of proteins. Several sequence pattern search...