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BMCBI
2008
87views more  BMCBI 2008»
13 years 7 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
BMCBI
2007
95views more  BMCBI 2007»
13 years 7 months ago
ZPS: visualization of recent adaptive evolution of proteins
Background: Detection of adaptive amino acid changes in proteins under recent short-term selection is of great interest for researchers studying microevolutionary processes in mic...
Sujay Chattopadhyay, Daniel E. Dykhuizen, Evgeni V...
BMCBI
2008
160views more  BMCBI 2008»
13 years 7 months ago
A comparison of four clustering methods for brain expression microarray data
Background: DNA microarrays, which determine the expression levels of tens of thousands of genes from a sample, are an important research tool. However, the volume of data they pr...
Alexander L. Richards, Peter Holmans, Michael C. O...
BMCBI
2008
103views more  BMCBI 2008»
13 years 7 months ago
Discovering multi-level structures in bio-molecular data through the Bernstein inequality
Background: The unsupervised discovery of structures (i.e. clusterings) underlying data is a central issue in several branches of bioinformatics. Methods based on the concept of s...
Alberto Bertoni, Giorgio Valentini
AMC
2006
104views more  AMC 2006»
13 years 7 months ago
Three counterexamples refuting Kieu's plan for "quantum adiabatic hypercomputation"; and some uncomputable quantum mechanical ta
-- Tien D. Kieu, in 10 papers posted to the quant-ph section of the xxx.lanl.gov preprint archive [some of which were also published in printed journals such as Proc. Royal Soc. A ...
Warren D. Smith