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BMCBI
2007
104views more  BMCBI 2007»
13 years 7 months ago
TISs-ST: a web server to evaluate polymorphic translation initiation sites and their reflections on the secretory targets
Background: The nucleotide sequence flanking the translation initiation codon (start codon context) affects the translational efficiency of eukaryotic mRNAs, and may indicate the ...
Renato Vicentini, Marcelo Menossi
BMCBI
2007
153views more  BMCBI 2007»
13 years 7 months ago
MPHASYS: a mouse phenotype analysis system
Background: Systematic, high-throughput studies of mouse phenotypes have been hampered by the inability to analyze individual animal data from a multitude of sources in an integra...
R. Brent Calder, Rudolf B. Beems, Harry van Steeg,...
BMCBI
2008
166views more  BMCBI 2008»
13 years 7 months ago
Biclustering via optimal re-ordering of data matrices in systems biology: rigorous methods and comparative studies
Background: The analysis of large-scale data sets via clustering techniques is utilized in a number of applications. Biclustering in particular has emerged as an important problem...
Peter A. DiMaggio Jr., Scott R. McAllister, Christ...
BMCBI
2008
71views more  BMCBI 2008»
13 years 7 months ago
A tale of two symmetrical tails: Structural and functional characteristics of palindromes in proteins
Background: It has been previously shown that palindromic sequences are frequently observed in proteins. However, our knowledge about their evolutionary origin and their possible ...
Armita Sheari, Mehdi Kargar, Ali Katanforoush, Sha...
BMCBI
2008
159views more  BMCBI 2008»
13 years 7 months ago
Multivariate hierarchical Bayesian model for differential gene expression analysis in microarray experiments
Background: Identification of differentially expressed genes is a typical objective when analyzing gene expression data. Recently, Bayesian hierarchical models have become increas...
Hongya Zhao, Kwok-Leung Chan, Lee-Ming Cheng, Hong...