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» On the Approximability of Comparing Genomes with Duplicates
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JEA
2008
97views more  JEA 2008»
13 years 7 months ago
Approximating the true evolutionary distance between two genomes
As more and more genomes are sequenced, evolutionary biologists are becoming increasingly interested in evolution at the level of whole genomes, in scenarios in which the genome e...
Krister M. Swenson, Mark Marron, Joel V. Earnest-D...
WABI
2010
Springer
160views Bioinformatics» more  WABI 2010»
13 years 5 months ago
Genomic Distance with DCJ and Indels
The double cut and join (DCJ) operation, introduced by Yancopoulos, Attie and Friedberg in 2005, allows one to represent most rearrangement events in genomes. However, a DCJ cannot...
Marília D. V. Braga, Eyla Willing, Jens Sto...
FSTTCS
2003
Springer
14 years 23 days ago
Comparing Sequences with Segment Rearrangements
Computational genomics involves comparing sequences based on “similarity” for detecting evolutionary and functional relationships. Until very recently, available portions of th...
Funda Ergün, S. Muthukrishnan, Süleyman ...
RECOMB
2002
Springer
14 years 7 months ago
Tests for gene clustering
Comparing chromosomal gene order in two or more related species is an important approach to studying the forces that guide genome organization and evolution. Linked clusters of si...
Dannie Durand, David Sankoff
BMCBI
2007
89views more  BMCBI 2007»
13 years 7 months ago
Comparing segmentations by applying randomization techniques
Background: There exist many segmentation techniques for genomic sequences, and the segmentations can also be based on many different biological features. We show how to evaluate ...
Niina Haiminen, Heikki Mannila, Evimaria Terzi