As more and more genomes are sequenced, evolutionary biologists are becoming increasingly interested in evolution at the level of whole genomes, in scenarios in which the genome e...
Krister M. Swenson, Mark Marron, Joel V. Earnest-D...
The double cut and join (DCJ) operation, introduced by Yancopoulos, Attie and Friedberg in 2005, allows one to represent most rearrangement events in genomes. However, a DCJ cannot...
Computational genomics involves comparing sequences based on “similarity” for detecting evolutionary and functional relationships. Until very recently, available portions of th...
Comparing chromosomal gene order in two or more related species is an important approach to studying the forces that guide genome organization and evolution. Linked clusters of si...
Background: There exist many segmentation techniques for genomic sequences, and the segmentations can also be based on many different biological features. We show how to evaluate ...