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» On the Approximability of Comparing Genomes with Duplicates
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RECOMB
2008
Springer
14 years 7 months ago
Computation of Median Gene Clusters
Whole genome comparison based on gene order has become a popular approach in comparative genomics. An important task in this field is the detection of gene clusters, i.e. sets of g...
Sebastian Böcker, Katharina Jahn, Julia Mixta...
BMCBI
2010
133views more  BMCBI 2010»
13 years 7 months ago
Translog, a web browser for studying the expression divergence of homologous genes
Background: Increasing amount of data from comparative genomics, and newly developed technologies producing accurate gene expression data facilitate the study of the expression di...
Xianjun Dong, Altuna Akalin, Yogita Sharma, Boris ...
RECOMB
2010
Springer
13 years 5 months ago
Listing All Parsimonious Reversal Sequences: New Algorithms and Perspectives
In comparative genomics studies, finding a minimum length sequences of reversals, so called sorting by reversals, has been the topic of a huge literature. Since there are many mini...
Ghada Badr, Krister M. Swenson, David Sankoff
RECOMB
2008
Springer
14 years 7 months ago
Reconstructing the Evolutionary History of Complex Human Gene Clusters
Abstract. Clusters of genes that evolved from single progenitors via repeated segmental duplications present significant challenges to the generation of a truly complete human geno...
Adam C. Siepel, Eric D. Green, Giltae Song, Tom&aa...
ISAAC
2004
Springer
106views Algorithms» more  ISAAC 2004»
14 years 28 days ago
Minimum Common String Partition Problem: Hardness and Approximations
String comparison is a fundamental problem in computer science, with applications in areas such as computational biology, text processing or compression. In this paper we address t...
Avraham Goldstein, Petr Kolman, Jie Zheng