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NAR
2011
225views Computer Vision» more  NAR 2011»
12 years 10 months ago
IsoBase: a database of functionally related proteins across PPI networks
We describe IsoBase, a database identifying functionally related proteins, across five major eukaryotic model organisms: Saccharomyces cerevisiae, Drosophila melanogaster, Caenorh...
Daniel Park, Rohit Singh, Michael Baym, Chung-Shou...
BMCBI
2010
109views more  BMCBI 2010»
13 years 7 months ago
Functional characterization and topological modularity of molecular interaction networks
Background: Analyzing interaction networks for functional characterization poses significant challenges arising from the noisy, incomplete, and generic nature of both the interact...
Jayesh Pandey, Mehmet Koyutürk, Ananth Grama
NAR
2011
214views Computer Vision» more  NAR 2011»
12 years 10 months ago
DAnCER: Disease-Annotated Chromatin Epigenetics Resource
Chromatin modification (CM) is a set of epigenetic processes that govern many aspects of DNA replication, transcription and repair. CM is carried out by groups of physically inter...
Andrei L. Turinsky, Brian Turner, Rosanne C. Borja...
BMCBI
2007
144views more  BMCBI 2007»
13 years 7 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...
BMCBI
2005
99views more  BMCBI 2005»
13 years 7 months ago
Super paramagnetic clustering of protein sequences
Background: Detection of sequence homologues represents a challenging task that is important for the discovery of protein families and the reliable application of automatic annota...
Igor V. Tetko, Axel Facius, Andreas Ruepp, Hans-We...