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121
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BMCBI
2007
15 years 4 months ago
2007
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
161
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BMCBI
2007
15 years 4 months ago
2007
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
147
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BMCBI
2007
15 years 4 months ago
2007
Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...
172
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BMCBI
2007
15 years 4 months ago
2007
Background: To date more than 2,1 million gene products from more than 100000 different species have been described specifying their function, the processes they are involved in a...
145
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BMCBI
2007
15 years 4 months ago
2007
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...