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BMCBI
2010
98views more  BMCBI 2010»
13 years 8 months ago
A semi-nonparametric mixture model for selecting functionally consistent proteins
Background: High-throughput technologies have led to a new era of proteomics. Although protein microarray experiments are becoming more common place there are a variety of experim...
Lianbo Yu, R. W. Doerge
BMCBI
2008
103views more  BMCBI 2008»
13 years 8 months ago
Discovering multi-level structures in bio-molecular data through the Bernstein inequality
Background: The unsupervised discovery of structures (i.e. clusterings) underlying data is a central issue in several branches of bioinformatics. Methods based on the concept of s...
Alberto Bertoni, Giorgio Valentini
BMCBI
2010
165views more  BMCBI 2010»
13 years 8 months ago
Bayesian integrated modeling of expression data: a case study on RhoG
Background: DNA microarrays provide an efficient method for measuring activity of genes in parallel and even covering all the known transcripts of an organism on a single array. T...
Rashi Gupta, Dario Greco, Petri Auvinen, Elja Arja...
BMCBI
2007
147views more  BMCBI 2007»
13 years 8 months ago
Statistical significance of quantitative PCR
Background: PCR has the potential to detect and precisely quantify specific DNA sequences, but it is not yet often used as a fully quantitative method. A number of data collection...
Yann Karlen, Alan McNair, Sébastien Persegu...
BMCBI
2008
149views more  BMCBI 2008»
13 years 6 months ago
MD-SeeGH: a platform for integrative analysis of multi-dimensional genomic data
Background: Recent advances in global genomic profiling methodologies have enabled multidimensional characterization of biological systems. Complete analysis of these genomic prof...
Bryan Chi, Ronald J. deLeeuw, Bradley P. Coe, Raym...