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» Ontology consolidation in bioinformatics
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BMCBI
2008
123views more  BMCBI 2008»
13 years 7 months ago
Functional module detection by functional flow pattern mining in protein interaction networks
eraction networks. In this abstract, we extend this approach by mining functional flow patterns for the purpose of detecting small-sized modules for specific functions. Methods Our...
Young-Rae Cho, Lei Shi, Aidong Zhang
BMCBI
2008
184views more  BMCBI 2008»
13 years 7 months ago
Integrating protein-protein interactions and text mining for protein function prediction
Background: Functional annotation of proteins remains a challenging task. Currently the scientific literature serves as the main source for yet uncurated functional annotations, b...
Samira Jaeger, Sylvain Gaudan, Ulf Leser, Dietrich...
BMCBI
2006
128views more  BMCBI 2006»
13 years 7 months ago
Comparative assessment of performance and genome dependence among phylogenetic profiling methods
Background: The rapidly increasing speed with which genome sequence data can be generated will be accompanied by an exponential increase in the number of sequenced eukaryotes. Wit...
Evan S. Snitkin, Adam M. Gustafson, Joseph C. Mell...
BMCBI
2007
121views more  BMCBI 2007»
13 years 7 months ago
e-Science and biological pathway semantics
Background: The development of e-Science presents a major set of opportunities and challenges for the future progress of biological and life scientific research. Major new tools a...
Joanne S. Luciano, Robert D. Stevens
BMCBI
2007
99views more  BMCBI 2007»
13 years 7 months ago
Towards validating the hypothesis of phylogenetic profiling
Background: As the number of fully sequenced genome increases, the need is greater for bioinformatics to predict or annotate genes of a newly sequenced genome. Ever since Eisenber...
Raja Loganantharaj, Mazen Atwi