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BMCBI
2007
130views more  BMCBI 2007»
15 years 4 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
BMCBI
2007
104views more  BMCBI 2007»
15 years 4 months ago
TISs-ST: a web server to evaluate polymorphic translation initiation sites and their reflections on the secretory targets
Background: The nucleotide sequence flanking the translation initiation codon (start codon context) affects the translational efficiency of eukaryotic mRNAs, and may indicate the ...
Renato Vicentini, Marcelo Menossi
ALGORITHMICA
2006
86views more  ALGORITHMICA 2006»
15 years 4 months ago
Slabpose Columnsort: A New Oblivious Algorithm for Out-of-Core Sorting on Distributed-Memory Clusters
Our goal is to develop a robust out-of-core sorting program for a distributed-memory cluster. The literature contains two dominant paradigms for out-of-core sorting algorithms: me...
Geeta Chaudhry, Thomas H. Cormen
BMCBI
2006
102views more  BMCBI 2006»
15 years 4 months ago
UVPAR: fast detection of functional shifts in duplicate genes
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
Vicente Arnau, Miguel Gallach, J. Ignasi Lucas, Ig...
BMCBI
2006
202views more  BMCBI 2006»
15 years 4 months ago
Spectral embedding finds meaningful (relevant) structure in image and microarray data
Background: Accurate methods for extraction of meaningful patterns in high dimensional data have become increasingly important with the recent generation of data types containing ...
Brandon W. Higgs, Jennifer W. Weller, Jeffrey L. S...