2131 search results - page 386 / 427 » Optimal Difference Operator Selection |
137
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HIS
2007
15 years 3 months ago
2007
—Machine learning is inherently a multiobjective task. Traditionally, however, either only one of the objectives is adopted as the cost function or multiple objectives are aggreg...
123
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BMCBI
2008
15 years 2 months ago
2008
Background: A key goal of drug discovery is to increase the throughput of small molecule screens without sacrificing screening accuracy. High-throughput screening (HTS) in drug di...
110
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BMCBI
2008
15 years 2 months ago
2008
Background: As a rule, peptides are more flexible and unstructured than proteins with their substantial stabilizing hydrophobic cores. Nevertheless, a few stably folding peptides ...
101
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BMCBI
2006
15 years 2 months ago
2006
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
131
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BMCBI
2007
15 years 2 months ago
2007
Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...