327 search results - page 16 / 66 » Optimal detection of sequence similarity by local alignment |
BMCBI
2010
13 years 7 months ago
2010
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
BMCBI
2008
13 years 7 months ago
2008
Background: Identification of RNA homologs within genomic stretches is difficult when pairwise sequence identity is low or unalignable flanking residues are present. In both cases...
BMCBI
2007
13 years 7 months ago
2007
Background: Sequence comparison faces new challenges today, with many complete genomes and large libraries of transcripts known. Gene annotation pipelines match these sequences in...
RECOMB
2003
Springer
14 years 8 months ago
2003
Springer
Large-scale comparison of genomic DNA is of fundamental importance in annotating functional elements of genomes. To perform large comparisons efficiently, BLAST (Methods: Companio...
WABI
2007
Springer
14 years 1 months ago
2007
Springer
Abstract. Protein structural alignment is an indispensable tool used for many different studies in bioinformatics. Most structural alignment algorithms assume that the structural ...