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» Optimization Multiple Sequence Alignment Scheme in DC-BTA
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RECOMB
1997
Springer
14 years 20 days ago
A more efficient approximation scheme for tree alignment
We present a new polynomial time approximation scheme (PTAS) for tree alignment, which is an important variant of multiple sequence alignment. As in the existing PTASs in the liter...
Lusheng Wang, Tao Jiang, Dan Gusfield
BMCBI
2004
96views more  BMCBI 2004»
13 years 8 months ago
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
Olga V. Matveeva, Brian T. Foley, Vladimir A. Nemt...
WABI
2004
Springer
106views Bioinformatics» more  WABI 2004»
14 years 1 months ago
Suboptimal Local Alignments Across Multiple Scoring Schemes
Abstract. Sequence alignment algorithms have a long standing tradition in bioinformatics. In this paper, we formulate an extension to existing local alignment algorithms: local ali...
Morris Michael, Christoph Dieterich, Jens Stoye
BMCBI
2006
139views more  BMCBI 2006»
13 years 8 months ago
Improvement in accuracy of multiple sequence alignment using novel group-to-group sequence alignment algorithm with piecewise li
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...
Shinsuke Yamada, Osamu Gotoh, Hayato Yamana
BMCBI
2007
153views more  BMCBI 2007»
13 years 8 months ago
Lower bounds on multiple sequence alignment using exact 3-way alignment
Background: Multiple sequence alignment is fundamental. Exponential growth in computation time appears to be inevitable when an optimal alignment is required for many sequences. E...
Charles J. Colbourn, Sudhir Kumar