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» Optimizing amino acid groupings for GPCR classification
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BMCBI
2010
151views more  BMCBI 2010»
13 years 8 months ago
Classification of G-protein coupled receptors based on support vector machine with maximum relevance minimum redundancy and gene
Background: Because a priori knowledge about function of G protein-coupled receptors (GPCRs) can provide useful information to pharmaceutical research, the determination of their ...
Zhanchao Li, Xuan Zhou, Zong Dai, Xiaoyong Zou
BMCBI
2007
135views more  BMCBI 2007»
13 years 8 months ago
Sequence similarity is more relevant than species specificity in probabilistic backtranslation
Background: Backtranslation is the process of decoding a sequence of amino acids into the corresponding codons. All synthetic gene design systems include a backtranslation module....
Alfredo Ferro, Rosalba Giugno, Giuseppe Pigola, Al...
BMCBI
2008
170views more  BMCBI 2008»
13 years 8 months ago
A genetic approach for building different alphabets for peptide and protein classification
Background: In this paper, it is proposed an optimization approach for producing reduced alphabets for peptide classification, using a Genetic Algorithm. The classification task i...
Loris Nanni, Alessandra Lumini
APBC
2004
125views Bioinformatics» more  APBC 2004»
13 years 10 months ago
A Dihedral Angle Database of Short Sub-sequences for Protein Structure Prediction
Protein structure prediction is considered to be the holy grail of bioinformatics. Ab initio and homology modelling are two important groups of methods used in protein structure p...
Saravanan Dayalan, Savitri Bevinakoppa, Heiko Schr...
JIB
2007
172views more  JIB 2007»
13 years 8 months ago
The ABC (Analysing Biomolecular Contacts)-database
As protein-protein interactions are one of the basic mechanisms in most cellular processes, it is desirable to understand the molecular details of protein-protein contacts and ult...
Peter Walter, Sam Ansari, Volkhard Helms