We introduce a model of DNA sequence evolution which can account for biases in mutation rates that depend on the identity of the neighboring bases. An analytic solution for this c...
Using a flexible representation of biological sequences, we have performed a comparative analysis of 1208 known tRNA sequences. We believe we our technique is a more sensitive met...
Grid and distributed public computing schemes has become an essential tool for many scientific fields including bioinformatics, computational biology and systems biology. The adopt...
DNA sequences and their annotations form ever expanding data sets. Proper explorations of such data sets require new tools for visualization and analysis. In this case study, we h...
Tim H. J. M. Peeters, Huub van de Wetering, Mark W...
Motivation: Next-generation sequencing methods are generating increasingly massive datasets, yet still do not fully capture genetic diversity in the richest environments. To under...
Alex L. B. Leach, James P. J. Chong, Kelly R. Rede...