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» Parallel Computation in Biological Sequence Analysis
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WABI
2001
Springer
162views Bioinformatics» more  WABI 2001»
14 years 9 days ago
A Simple Hyper-Geometric Approach for Discovering Putative Transcription Factor Binding Sites
A central issue in molecular biology is understanding the regulatory mechanisms that control gene expression. The recent flood of genomic and postgenomic data opens the way for co...
Yoseph Barash, Gill Bejerano, Nir Friedman
NAR
2011
188views Computer Vision» more  NAR 2011»
12 years 10 months ago
NCBI Epigenomics: a new public resource for exploring epigenomic data sets
The Epigenomics database at the National Center for Biotechnology Information (NCBI) is a new resource that has been created to serve as a comprehensive public resource for whole-...
Ian M. Fingerman, Lee McDaniel, Xuan Zhang, Walter...
BMCBI
2008
145views more  BMCBI 2008»
13 years 8 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
ICCAD
2009
IEEE
147views Hardware» more  ICCAD 2009»
13 years 5 months ago
SAT-based protein design
Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
Noah Ollikainen, Ellen Sentovich, Carlos Coelho, A...
GRID
2006
Springer
13 years 8 months ago
Grid Deployment of Legacy Bioinformatics Applications with Transparent Data Access
Although grid computing offers great potential for executing large-scale bioinformatics applications, practical deployment is constrained by legacy interfaces. Most widely deployed...
Christophe Blanchet, Rémi Mollon, Douglas T...