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» Parallel Extreme Pathway Computation for Metabolic Networks
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CMPB
2010
171views more  CMPB 2010»
13 years 5 months ago
Metabolica: A statistical research tool for analyzing metabolic networks
Steady state flux balance analysis (FBA) for cellular metabolism is used, e.g., to seek information on the activity of the different pathways under equilibrium conditions, or as a...
Jenni Heino, Daniela Calvetti, Erkki Somersalo
CLADE
2008
IEEE
14 years 5 months ago
SWARM: a scientific workflow for supporting bayesian approaches to improve metabolic models
With the exponential growth of complete genome sequences, the analysis of these sequences is becoming a powerful approach to build genome-scale metabolic models. These models can ...
Xinghua Shi, Rick Stevens
BMCBI
2011
13 years 5 months ago
Context-dependent transcriptional regulations between signal transduction pathways
Background: Cells coordinate their metabolism, proliferation, and cellular communication according to environmental cues through signal transduction. Because signal transduction h...
Sohyun Hwang, Sangwoo Kim, Heesung Shin, Doheon Le...
BMCBI
2007
93views more  BMCBI 2007»
13 years 11 months ago
The topology of metabolic isotope labeling networks
Background: Metabolic Flux Analysis (MFA) based on isotope labeling experiments (ILEs) is a widely established tool for determining fluxes in metabolic pathways. Isotope labeling ...
Michael Weitzel, Wolfgang Wiechert, Katharina N&ou...
EVOW
2009
Springer
13 years 8 months ago
Evolutionary Approaches for Strain Optimization Using Dynamic Models under a Metabolic Engineering Perspective
One of the purposes of Systems Biology is the quantitative modeling of biochemical networks. In this effort, the use of dynamical mathematical models provides for powerful tools in...
Pedro Evangelista, Isabel Rocha, Eugénio C....