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122
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SC
2003
ACM
15 years 7 months ago
A Million-Fold Speed Improvement in Genomic Repeats Detection
This paper presents a novel, parallel algorithm for generating top alignments. Top alignments are used for finding internal repeats in biological sequences like proteins and gene...
John W. Romein, Jaap Heringa, Henri E. Bal
BMCBI
2007
117views more  BMCBI 2007»
15 years 2 months ago
Supervised multivariate analysis of sequence groups to identify specificity determining residues
Background: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper ...
Iain M. Wallace, Desmond G. Higgins
RECOMB
2006
Springer
16 years 2 months ago
Detecting the Dependent Evolution of Biosequences
Abstract. A probabilistic graphical model is developed in order to detect the dependent evolution between different sites in biological sequences. Given a multiple sequence alignme...
Jeremy Darot, Chen-Hsiang Yeang, David Haussler
RECOMB
2003
Springer
16 years 2 months ago
A multi-expert system for the automatic detection of protein domains from sequence information
We describe a novel method for detecting the domain structure of a protein from sequence information alone. The method is based on analyzing multiple sequence alignments that are ...
Niranjan Nagarajan, Golan Yona
118
Voted
BMCBI
2006
108views more  BMCBI 2006»
15 years 2 months ago
RibAlign: a software tool and database for eubacterial phylogeny based on concatenated ribosomal protein subunits
Background: Until today, analysis of 16S ribosomal RNA (rRNA) sequences has been the de-facto gold standard for the assessment of phylogenetic relationships among prokaryotes. How...
Hanno Teeling, Frank Oliver Glöckner