115 search results - page 10 / 23 » Parameters for accurate genome alignment |
NAR
2011
12 years 10 months ago
2011
Gene duplications are scattered widely throughout the human genome. A single-base difference located in nearly identical duplicated segments may be misjudged as a single nucleotid...
BMCBI
2010
13 years 7 months ago
2010
Background: Sequence alignments form part of many investigations in molecular biology, including the determination of phylogenetic relationships, the prediction of protein structu...
RECOMB
2007
Springer
14 years 7 months ago
2007
Springer
Abstract. Sequence to structure alignment is an important step in homology modeling of protein structures. Incorporation of features like secondary structure, solvent accessibility...
BMCBI
2010
13 years 7 months ago
2010
Background: With the continued development of new computational tools for multiple sequence alignment, it is necessary today to develop benchmarks that aid the selection of the mo...
RECOMB
2008
Springer
14 years 7 months ago
2008
Springer
Understanding the variation of recombination rates across a given genome is crucial for disease gene mapping and for detecting signatures of selection, to name just a couple of app...