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» Pathline: A Tool For Comparative Functional Genomics
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WOB
2003
129views Bioinformatics» more  WOB 2003»
13 years 9 months ago
Procsimo: uma Ferramenta de Procura de Similaridade entre Operons
In this work, we propose a software tool, called PROCSIMO, which aims the identification of similarities between operons in bacterial genomes. From a database which contains the ch...
Carlos Azevedo, Alexandre Plastino, Ana Tereza R. ...
BMCBI
2005
121views more  BMCBI 2005»
13 years 7 months ago
Automated methods of predicting the function of biological sequences using GO and BLAST
Background: With the exponential increase in genomic sequence data there is a need to develop automated approaches to deducing the biological functions of novel sequences with hig...
Craig E. Jones, Ute Baumann, Alfred L. Brown
BMCBI
2008
200views more  BMCBI 2008»
13 years 7 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
BMCBI
2006
87views more  BMCBI 2006»
13 years 7 months ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen
NAR
2010
143views more  NAR 2010»
13 years 2 months ago
WormBase: a comprehensive resource for nematode research
WormBase (http://www.wormbase.org) is a central data repository for nematode biology. Initially created as a service to the Caenorhabditis elegans research field, WormBase has evo...
Todd W. Harris, Igor Antoshechkin, Tamberlyn Bieri...