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» Pathway Logic Modeling of Protein Functional Domains in Sign...
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CSB
2003
IEEE
14 years 4 months ago
Pathway Logic Modeling of Protein Functional Domains in Signal Transduction
Carolyn L. Talcott, Steven Eker, Merrill Knapp, Pa...
BMCBI
2006
122views more  BMCBI 2006»
13 years 11 months ago
A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
Holger Conzelmann, Julio Saez-Rodriguez, Thomas Sa...
BMCBI
2005
109views more  BMCBI 2005»
13 years 10 months ago
Automation of gene assignments to metabolic pathways using high-throughput expression data
Background: Accurate assignment of genes to pathways is essential in order to understand the functional role of genes and to map the existing pathways in a given genome. Existing ...
Liviu Popescu, Golan Yona
BMCBI
2010
127views more  BMCBI 2010»
13 years 11 months ago
PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactom
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...
BMCBI
2008
120views more  BMCBI 2008»
13 years 11 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...