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» Pattern Matching in Degenerate DNA RNA Sequences
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BMCBI
2008
90views more  BMCBI 2008»
13 years 7 months ago
Genome-scale study of the importance of binding site context for transcription factor binding and gene regulation
Background: The rate of mRNA transcription is controlled by transcription factors that bind to specific DNA motifs in promoter regions upstream of protein coding genes. Recent res...
Jakub Orzechowski Westholm, Feifei Xu, Hans Ronne,...
RECOMB
2001
Springer
13 years 12 months ago
Edit distance between two RNA structures
The primary structure of a ribonucleic acid (RNA) molecule is a sequence of nucleotides (bases) over the four-letter alphabet fA; C; G; Ug. The secondary or tertiary structure of ...
Guohui Lin, Bin Ma, Kaizhong Zhang
BMCBI
2006
88views more  BMCBI 2006»
13 years 7 months ago
RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes
Background: RNA-dependent gene silencing is becoming a routine tool used in laboratories worldwide. One of the important remaining hurdles in the selection of the target sequence,...
Jean-François Lucier, Lucien Junior Bergero...
RECOMB
2004
Springer
14 years 7 months ago
Designing multiple simultaneous seeds for DNA similarity search
The challenge of similarity search in massive DNA sequence databases has inspired major changes in BLAST-style alignment tools, which accelerate search by inspecting only pairs of...
Yanni Sun, Jeremy Buhler
CPM
2005
Springer
206views Combinatorics» more  CPM 2005»
14 years 1 months ago
A Fast Algorithm for Approximate String Matching on Gene Sequences
Abstract. Approximate string matching is a fundamental and challenging problem in computer science, for which a fast algorithm is highly demanded in many applications including tex...
Zheng Liu, Xin Chen, James Borneman, Tao Jiang