38 search results - page 4 / 8 » Pfam: multiple sequence alignments and HMM-profiles of prote... |
BMCBI
2007
13 years 8 months ago
2007
Background: The relationship between divergence of amino-acid sequence and divergence of function among homologous proteins is complex. The assumption that homologs share function...
BMCBI
2006
2006
On single and multiple models of protein families for the detection of remote sequence relationships
13 years 8 months ago
Background: The detection of relationships between a protein sequence of unknown function and a sequence whose function has been characterised enables the transfer of functional a...
BMCBI
2002
13 years 8 months ago
2002
Background: Most profile and motif databases strive to classify protein sequences into a broad spectrum of protein families. The next step of such database studies should include ...
NAR
2006
13 years 8 months ago
2006
Phylogenetic analysis and examination of protein domains allow accurate genome annotation and are invaluable to study proteins and protein complex evolution. However, two sequence...
BMCBI
2005
13 years 8 months ago
2005
Background: Whole-genome sequencing projects are rapidly producing an enormous number of new sequences. Consequently almost every family of proteins now contains hundreds of membe...